NAD+ Liposomal Anti Aging Supplement Complex AEON with Nicotinamide DUO™
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AEON™ is the World’s best anti-aging supplement and the only one that contains a full spectrum 11-compound complex. Each dose consists of two easy to swallow capsules that contain:
*This products formulation is kept up to date with the latest longevity research so the formula/ingredients may change slightly without notice.
Testing for heavy metals, contaminants, and potency is conducted on all raw materials, and randomly on finished product by in-house, and 3rd party laboratories yearly. Please email us to view the most recent report.
Don’t want to subscribe to monthly delivery? Now you have the option of purchasing a full years worth of AEON (12 bottles), at a 30% discount.
Just add AEON to your cart, and adjust the quantity to 12.
When you checkout, a 30% discount will be applied automatically to your order.
Compounds in AEON™:
Nicotinamide DUO™ is a proprietary NAD+ precursor developed by Perpetua.Life® Biotech based on a an 80/20 blend of Mono/Riboside (LNR) which has been found to boost NAD+ level even higher than Riboside alone.
NAD+ is a compound found in every cell in your body and involved in many critical processes, including energy metabolism, DNA repair, and gene expression (22, 23).
NAD+ levels decline with age, and this decline is thought to be associated with accelerated physical decline and the onset of age-related diseases like Alzheimer’s (23).
Studies have shown that supplementing with NAD+ precursors like NR restores NAD+ levels and prevents age-related physical decline (24)
For example, a study in aging subjects demonstrated that supplementing orally with Nicotinamide Mono prevented age-associated genetic changes and improved energy metabolism, physical activity, and insulin sensitivity (24B).
A 2019 study in 12 men with an average age of 75 showed that supplementing with up to 1 gram of Nicotinamide daily for 21 days increased NAD+ levels in skeletal muscle and reduced levels of inflammatory proteins in the body (25).
Fisetin is a flavonoid compound that’s considered a senotherapeutic, meaning it can kill senescent cells.
Fisetin as an anticancer agent targeting the growth signaling pathways (F01).
Fisetin and Quercetin: Promising Flavonoids with Chemopreventive Potential (F03).
Quercetin: A functional dietary flavonoid with potential chemo-preventive properties in colorectal cancer (Q3).
A preliminary investigation demonstrating the effect of quercetin on the expression of genes related to cell-cycle arrest, apoptosis and xenobiotic metabolism in human CO115 colon-adenocarcinoma cells using DNA microarray (Q4).
Quercetin, caffeic acid and Resveratrol regulate circadian clock genes and aging-related genes in young and old human lung fibroblast cells (Q4).
Resveratrol is a polyphenol in grapes, berries, peanuts, and red wine that may promote longevity by activating certain genes called sirtuins. It has been shown to increase the lifespan of fruit flies, yeasts, and nematodes (42).
Effects of Resveratrol and other Polyphenols on Sirt1: Relevance to Brain Function During Aging (R4)
Resveratrol, an Nrf2 activator, alleviates aging-related progressive renal injury (R3)
Role of resveratrol in regulation of cellular defense systems against oxidative stress (R2).
Effect of resveratrol and pterostilbene on aging and longevity (R1).
Resveratrol improves oxidative stress and prevents the progression of periodontitis via the activation of the Sirt1/AMPK and the Nrf2/antioxidant defense pathways in a periodontitis model (R5).
Quercetin, caffeic acid and Resveratrol regulate circadian clock genes and aging-related genes in young and old human lung fibroblast cells (Q4).
Astragalus membranaceus is a stress-reducing herb used in traditional Chinese medicine. It may help combat aging by reducing oxidative stress, promoting immune function, and preventing cellular damage (40).
Astragalus polysaccharide exerts anti-Parkinson via activating the PI3K/AKT/mTOR pathway to increase cellular autophagy level in vitro (A2).
Astragalus membranaceus: A Review of its Protection Against Inflammation and Gastrointestinal Cancers (A1).
Discovery of potent telomerase activators: Unfolding new therapeutic and anti-aging perspectives with astragalus (A3).
Experimental and clinical studies of mechanisms of the anti-aging effects of chemical compounds in Astragalus membranaceus (A4).
Astragalus (a traditional Chinese medicine) for treating chronic kidney disease (A5).
Epigallocatechin Gallate (EGCG)
Epigallocatechin gallate (EGCG) is a well-known polyphenol compound concentrated in green tea. It offers impressive health benefits, with research supporting its use to reduce the risk of certain cancers, as well as other health conditions like heart disease (9, 10, 11).
Among EGCG’s diverse array of potential health-promoting properties is its ability to promote longevity and protect against age-related disease development.
EGCG may slow aging by restoring mitochondrial function in cells and acting on pathways involved in aging, including the AMP-activated protein kinase signaling pathway (AMPK).
It also induces autophagy, the process by which your body removes damaged cellular material (12).
EGCG intake has been associated with a reduced risk of all-cause mortality, diabetes, stroke, and heart-disease-related death. Plus, animal studies have shown that it can protect against skin aging and wrinkles caused by ultraviolet (UV) light (13, 14, 15).
TMG has outstanding effects on controlling homocysteine levels in the blood. Homocysteine significantly increases around the middle stage of life, and it's linked to the development of heart disease and stroke.
In a breast cancer study, having more TMG in patients' diets was linked to fewer deaths from cancer [source].
In another study of more than 2800 lung cancer patients, high betaine intake was found to be protective against lung cancer [source].
A study including 193 senior citizens showed that an increase in TMG was linked to improvements in response time, memory, and brain function. People whose TMG levels went up the most also saw the most improvement in their memories [source].
Additionally, TMG is also being explored as treatment for other neurological disorders such as Alzheimer's disease [source].
L-theanine is an amino acid concentrated in certain teas, including green tea. It may help protect against mental decline and has been shown to extend the lifespan of roundworms by around 5% (35, 36).
l-Theanine attenuates liver aging by inhibiting advanced glycation end products in d-galactose-induced rats and reversing an imbalance of oxidative stress and inflammation (T1).
Protective Effect and Mechanism of Theanine on Lipopolysaccharide-Induced Inflammation and Acute Liver Injury (T2).
L-Theanine extends lifespan of adult Caenorhabditis elegans (T3).
The neuropharmacology of L-theanine(N-ethyl-L-glutamine): a possible neuroprotective and cognitive enhancing agent (T4).
l-Theanine Prevents Long-Term Affective and Cognitive Side Effects of Adolescent Δ-9-Tetrahydrocannabinol Exposure and Blocks Associated Molecular and Neuronal Abnormalities in the Mesocorticolimbic Circuitry (T5).
Spermidine has anti-inflammatory and anti-antioxidant properties, and can also enhance respiration and metabolic function. Increased dietary spermidine intake is thought to reduce the risk of diseases like cancer, metabolic disease, heart disease and neurodegeneration .
It can also improve memory and slow cognitive decline, as autophagy clears Alzheimer’s-causing amyloid-beta plaques in the brain and can thereby be used to prevent memory loss in older people suffering from mild dementia .
I feel much stronger and healthier… also my deep sleep qualifies improved, less wake up time for toilet from 3 to 1 time
You feel the difference in all areas -
Just wow! This is an amazing product. I can't believe how good it makes me feel.
I have been taking this for a month now and I do really feel a difference in my mental clarity and energy levels. I can actually feel my body producing more heat to keep me from getting cold/chills. I used to always wear warm clothes during the cold winters here and I am now more comfortable wearing lighter garments in the same temperatures. I feel this is evidence that I am creating more energy and burning my body's own fuel to help keep warm. I look forward to seeing how this progresses over a longer time frame. So far, I am impressed.
Aeon will make you feel younger because of the energy it gives the body. It also gave me a healthy appetite. I want to see more positive things this would give as I continue to take it.
It’s so far been a good product.
I’ve only been on it for 2 weeks but I can feel some improvement in my overall health .
Into my first month, and so far so good…
Very well balanced, strong and potent. Using it for more than a year and seeing results
Paid a fortune and was charged USD 25 on top for customs.
Very impressed at ingredients, customer support, and even packaging is impressive! Looking forward to seeing the results
I like it. Will reorder
Beng Huat C.
Took the recommended dosage of 2 capsules a day is not good enough. Added 1 more capsule and felt great.
Feeling better already!
I searched for a NAD-Supplement. This one also has Resveratrol , Fisetin and Quercitin along with Spermidin. The best I can get.
I've been on this for nearly two weeks and my joint pain is gone, I have more energy and i feel like I'm way less forgetful. Also the customer service is great! For some odd reason my order was sent to an address I no longer live at and they got a new one out to me right away. Super appreciate that.
Some ingredients would like a higher dose. The combination is great in that would be. A lot to chase down individual ingredients. Hence, convenient
After almost 3 weeks we noticed an increased level of energy. No side effects! We will return with more details after a longer period of use. Thank you Michael Morgan for your support! Best regards, Sorin Cucoranu
This is the most complete anti-aging supplement I have found. The combination of ingredients is unique and outstanding for including thise things that are proven. I have set up a subscription to be able to take this long term
I feel less tired, so waking up in the morning is less difficult. And my skin became a little firmer.
The best of best
Great product! Feel more energetic now than I've felt in years. Sleep is also improved and I feel like my skin is glowing. Overall happy with both the product and Perpetua.
I hope the promised health benefits will arrive - in the meantime I am happy that one sole pill contains all the necessary ingredients. Makes life easier!
I would say about of all these life extension supplements this is the best I have taken . I feel absolutely amazing and would most likely be buying more
Really like this supplement, havent been taking it but a couple weeks. Seems to be helping energy.
Funguje skvěle.Mám výbornou náladu, hodně energie a lépe spím.Opravdu to funguje !!!
Amazing. One of the best supplements I have ever taken. I have tried many products and this one makes a difference.
Seems to be great so far!
Seems to check all the boxes! Thanks
Most important bottle in the drawer
After 3 weeks, I feel more strength and endurance during my workouts. I still sometimes get a slump in my workdays, I hope that will go away too.
50 year old mother of a toddler.
As far as I can say it is that my wife told me that my skin seams to be more taunt. I use 2 capsules a day since 2 weeks.
Uncomfortable pins and needles itchy skin reaction lasted about 20 minutes initionally but was barely evident after 10th capsule.
I feel a bit more energy and a better general state. I will buy it again.
feel my receptors being repaired post overdose! very good for quitting smoking as well.
It's worth a penny! Feeling good about my self since I started taking this,no more tiredness everytime I wake up in the morning..Lots and lots of energy throughout the day,and a restful sleep at night. Loving this!!
Obsessed with this product! Game changer for me
Along with its other positive qualities, l think that this product helps with attentiveness and awareness during the course of your day.
If you believe the research then your NAD Level is dropping and you need to activate the sirtuins
I feel younger then my age with more energy. Super practical is to take only one pill with all the good ingredients.
One less star because I paid €40 tax (for 4 bottles in Croatia).
I have to be honest and say that I have changed my diet, I am exercising and I have almost finished the first bottle. I feel much better, sleep better, have more energy and my skin is much smoother.
nothing to say after a month of administration
I feel like I have much better focus and able to be more "on top of things".
Have not been taking it for more than 3 weeks but I do feel the difference.
I have also noticed that my skin has more glow - which is an added plus!
The best of the best
So far so great!! I've only been taking these for a week however my sleep pattern has never been better and my energy levels at work are more consistent. I will have a better review after my first bottle. I intend on staying on these as I'm hoping to see a positive change on my skin as I've incorporated some other great products as well!!
Too short to tell, I had to take it for a month to be able to say something.
Egy hónapja szedem párommal együtt a Longevity terméket, és az eddigi tapasztalataim kivétel nélkül csak jók.
56 éves vagyok, javult a bőröm, és a hajam minősége (dacára az ősz hajszálaknak). Energiaszintem látványosan nagyobb, és bevallom azt várom, hogy az alvásminőségem is javulni fog. Nagyszerű termék, bízom, bízunk benne❤️
I m 63 yo. I had loads of energy espy walking uphill to work, cognitive as well - my eyes were good, sharp n not tired from scanning small pixilated QR codes, plus were alert till bedtime. I’m very happy dunno why happy hormones I guess, now into my 2nd bottle.
My first bottle I used previous version only now the upgraded version. I can sleep easily. Awesome my hair can grow better.
On my sixth month so I should see improvements by now but have not really seen any change. The gold standard for me is if someone I haven't seen for a while remarks on how much healthier/better I'm looking ... sadly, that has not happened. Sometimes, if I don't feel any different, it helps to get sincere, unsolicited input from other people.
Still, it is hard to prove a negative so it continues to be a struggle over cost concerns (US$50/monthly is not insignificant) v. stopping a supplement and fearing things might go downhill even more.
The company is highly commended for outstanding customer service ... increasingly a rarity these days.
When I started on my August 2023 bottle, within a few minutes, my heart started palpitating, my entire body was itchy and flushed red, and I felt dizzy and sick. The sense of panic was terrifying. I'm in good physical shape and health but seriously thought I was going to have a stroke. I took to bed for a while but did not improve. I went downstairs to get my phone - which I had left on the kitchen table in my panic - to call my husband. Half way down the stairs (slowly, and holding tight to the banister), I was overwhelmed by dizziness and tumbled down the last 4-5 steps. My forehead was swollen, scratched and bruised for a few days, and still bears the marks of my fall - it will probably be a year before they fade. My husband was shocked that no bones were broken. I could easily have broken my neck with that kind of a fall.
I contacted Customer Service to cancel my subscription. Michael M promptly responded and was extremely helpful. He explained that the company had just reformulated the supplement to include B3. He offered to replace the new formulation with the old one. However, one of his explanations was puzzling ("... if you look in the description of AEON, you’ll see a notice saying the formulation is dynamic.") How can the typical customer be expected to know what "dynamic formulation" means? Also, my eyesight is pretty good but there is NO way any person with decent/normal eyesight can read anything on the bottle label.
I really wish prior warning about the side effects of the new formulation had been provided. I think the company erred by not informing customers in advance that it had reformulated its ingredients and the possible side effects. I am particularly sensitive to certain supplements and have extreme reactions to them. The whole alarming experience could have been avoided.
One of the replacement bottles came with the seal damaged (a gaping big hole in the center) so Michael promptly sent a re-replacement.
I will try the old formulation again but still haven't decided how long I will continue taking the supplements as - unlike many of the reviews (one of the reasons why I decided to take the plunge) - I have not seen the results the lucky people wrote about!
OK so far, feel still a little side effect because of B3. Otherwise OK.
I have two concerns.
The pills gives you a rash and makes you very red just after you have taken them.
Secondly I live in Europe and you pay a big fee in administration because you don’t declare and pay vat and tax. The actual amount is very small but the administration fee is huge.
Hello, About ten days ago I received the product. For the first seven days I only took one pill a day. Thanks to your warning I was not worried about the side effects. I have noticed that if I take the product without food the side effects show up. But I stress again that I have no problem with them. For the last three days I have been taking two pills each - one at lunch and one in the evening. I don't know exactly what to expect in terms of results and effects from the product, but I'm thinking of giving it a chance for six months. Simultaneously with it, I also take another product for erection problems - vigrix turbo, which contains the following ingredients: - Korean Ginseng root 90 mg; - Saw Palmetto berry 40 mg; - Gingko Biloba leaf 60 mg; - Hawthorn Berry 40 mg; - Epimedium leaf 40 mg; -
Tribulus Terrestis leaf 80 mg; - L-arginine 120 mg; - Vitamin B3 20 mg NE; - Vitamin B6 2 mg; - Selenium 50 mcg; - Zinc Gluconate-elemental Zink 8.4mg 60 mg, two pills a day. I hope I have been helpful. If you have any tips for me, please share them. Greetings
I feel more energetic and I am hoping that my peripheral neuropathy and Type 2 Diabetes can go away...
Also introducing supplement to my husband.
Start seeing my skin healthier, in two weeks of use.
Dr. Jirakorn T.
Kinda like it but it would need to take another longer so that I can feel more of its quality. But so far so good
Jūratė Marytė B.
I'm taking supplements for the third week. For the first few days, the skin on the face and body was very red and burning, so I took an aspirin 35 minutes before the first week. Now there is no need to drink aspirin anymore, because the redness of the face is very short (a few minutes) and is not tiring. More strength and joy in life appeared.
I have been feeling much better and have placed orders for my continuous benefits. Thanks team. Regards Jesu
If you want me to write a review give me a discount. My time is worth something , throw the dog a bone
I have had dr's tell me the ingredients are very helpful for brain restore... I am positive results .
My skin looks younger.
Taking it myself and giving it to my senior dog (soon 15 y), she is so much more energetic with the supplement!
yosef samon s.
first time use AEON, my energy increase. sleep better.
i like AEON, and will consume it forever
I purchase Aeon it’s been 3 weeks now and I must say it works , I am 63 years old and the first thing I have noticed is that my skin has a more youthful appearance. it’s also helped me more with energy levels, I highly recommend this complex .
Még kevés ideje szedem ahhoz, hogy igazánvéleményt alkothassak. Ám annyi bizonyos, hogy jobb az àllóképességem.
I am in a trial period, so I do not have too many experiences.
I’ve been taking the PERPETUA.LIFE Anti-Aging Supplement NAD+ Complex since December of 2022 and it is amazing!! My hypertension is under control (down from 150+/90 to 110/80) and my total cholesterol went from 240 down to 118! And my muscle development and energy levels have been so positively affected that I am able to work out harder and longer. I take 1 gram per day (2 capsules) as directed and absolutely love all of the great anti-aging ingredients!! Awesome product.
I have not really seen or felt different from using this yet but shipping was quick and no problems with delivery. I’m hoping to feel different by the time I’m done with the bottle. There was a few pills opened and spilled inside the bottle otherwise I would have given 5 stars. But as I said, not used long enough yet.
i’ve only been using this product less than a month. It’s too soon to tell how I’m feeling, but if I had to say better, I would say better. Still too soon to tell.
I have been taking only for 2 weeks. Nothing negative. But I am going to take it for next few months and see the results.
I love it. I’m feeling better each day
Just started using it and I feel pretty good. I will report more after a longer period.
Adriana, I hope you see this, I live in Rome and boxes mailed to me don’t come to my address either. I get a notice to pick it up at a certain Poste Italiane because they want to charge Customs. This fee depends on the value of the contents. I’ve already paid 12 € for a pair of fuzzy slippers a friend sent me and 22 € for a Christmas stocking cap, novelty earrings and a few other trinkets. Customs are quite high in Italy. It’s not the company doing this, it’s the foreign post office.
So far, so good. I'm still alive, so it must be working
After several months of taking AEON I stared t fee the positive effects. Friends that have not seen me for more than a year, said you look the same and what are you doing.
One is now taking the Supplement.
I stopped for almost months while my kidney was being treated.
I restarted after my Kidney sufficiently recovered.
I on AEON again.
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Zoltan Janos K.
Great customer service team
Although it is too short a period for evaluation, my experience with Aeon during the first two weeks is positive. I have better sleep and more energy. My skin seems tighter and I psychologically react better to stress.
Massive improvement in my skin and general health
I am 83. Been using AEON for a month. My energy levels have increased greatly. Before AEON I walked 2-3 miles most days, often I didn't really feel up to it. Now I walk 4-5+ miles a
day looking forward to my walks. Also I spent 15-20 minutes daily working with 5 pound weights.
Have a great day
So far, it's been a couple of weeks. When I remember to take it, it seems to boost energy and good overall body feel. Will update in the future.
Quick delivery, good product, exactly as expectations.
Love the ingredients! Early days for me 2 weeks in but I’m going to keep taking it
Although to soon to feel; I know the ingredients are working on a cellular level.
Absolutely love this product, I’ve tons of energy since I started taking it! Will definitely order another bottle soon
Been taking it for a little over a month. Definitely feel more energy throughout the day and into the evening. I’m going to keep using it!
I seem to be less tired, but it is still early days. I will monitor and provide feedback after a few months.
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